The United boss has selected a blend of experience and youth for the visits to Thailand, Australia, Japan and Hong Kong, while three other first-team stars - Robin van Persie, David De Gea and Shinji Kagawa - will join up with the rest of the squad later this month.
The players arrived at the airport at around 1pm in time for the flight approximately two hours later.
Among them was Wayne Rooney, who has been strongly linked with a move away from Old Trafford this summer, possibly to Premier League rivals Chelsea.

For now though he remains a United player and he is likely to feature in United's first pre-season work-out against the Singha All Star XI in Bangkok on Saturday.